IMPDH1 antibody (AA 123-500) (Cy3)

Catalog No. ABIN7999623

This Rabbit Polyclonal antibody specifically detects IMPDH1 in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for IMPDH1 antibody (AA 123-500) (Cy3) (ABIN7999623)

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-IMPDH1 Antibody (Cy3)

Binding Specificity: AA 123-500

Purpose: Anti-IMPDH1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IMPDH1 recombinant protein (Position: P123-E500).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Alternative Name: IMPDH1

Background:

Background: Inosine-5'-monophosphate dehydrogenase 1, also known as IMP dehydrogenase 1, is an enzyme that in humans is encoded by the IMPDH1 gene. The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: inosine monophosphate dehydrogenase 1

Gene ID: 3614

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process