IRS4 antibody (AA 145-1077) (Fluoro488)

Catalog No. ABIN7999924

The Fluoro488-conjugated Rabbit Polyclonal anti-IRS4 antibody (ABIN7999924) specifically detects IRS4 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IRS4 antibody (AA 145-1077) (Fluoro488) (ABIN7999924)

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS4 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-IRS4 Antibody (Fluoro488)

Binding Specificity: AA 145-1077

Purpose: Anti-IRS4 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human IRS4 shares 77.6% amino acid (aa) sequence identity with mouse IRS4.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IRS4 recombinant protein (Position: R145-E1077). Human IRS4 shares 77.6% amino acid (aa) sequence identity with mouse IRS4.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IRS4

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Alternative Name: IRS4

Background:

Background: Insulin receptor substrate 4 is a protein that in humans is encoded by the IRS4 gene. IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.

Gene Full Name: insulin receptor substrate 4

Gene ID: 8471

UniProt: O14654