INTS12 antibody (AA 1-384) (Fluoro488)

Catalog No. ABIN8000255

This Rabbit Polyclonal antibody specifically detects INTS12 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for INTS12 antibody (AA 1-384) (Fluoro488) (ABIN8000255)

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS12 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-INTS12 Antibody (Fluoro488)

Binding Specificity: AA 1-384

Purpose: Anti-INTS12 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human INTS12 shares 91.1%,90.6% amino acid (aa) sequence identity with mouse,rat INTS12,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human INTS12 recombinant protein (Position: M1-K384). Human INTS12 shares 91.1% and 90.6% amino acid (aa) sequence identity with mouse and rat INTS12, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for INTS12

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Alternative Name: INTS12

Background:

Background: Integrator complex subunit 12 (Int12) also known as PHD finger protein 22 (PHF22) is a protein that in humans is encoded by the INTS12 gene. INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).

Gene Full Name: integrator complex subunit 12

Gene ID: 57117

UniProt: Q96CB8