INTS12 antibody (AA 1-384)

Catalog No. ABIN8000263

The Rabbit Polyclonal anti-INTS12 antibody (ABIN8000263) specifically detects INTS12 in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for INTS12 antibody (AA 1-384) (ABIN8000263)

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-INTS12 Antibody

Binding Specificity: AA 1-384

Purpose: Anti-INTS12 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human INTS12 shares 91.1%,90.6% amino acid (aa) sequence identity with mouse,rat INTS12,respectively.

Characteristics: Anti-INTS12 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human INTS12 recombinant protein (Position: M1-K384). Human INTS12 shares 91.1% and 90.6% amino acid (aa) sequence identity with mouse and rat INTS12, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for INTS12

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Alternative Name: INTS12

Background:

Background: Integrator complex subunit 12 (Int12) also known as PHD finger protein 22 (PHF22) is a protein that in humans is encoded by the INTS12 gene. INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).

Gene Full Name: integrator complex subunit 12

Molecular Weight: 68 kDa

Gene ID: 57117

UniProt: Q96CB8