ITGA2 antibody (AA 285-1181) (Fluoro550)

Catalog No. ABIN8000311

The Fluoro550-conjugated Rabbit Polyclonal anti-ITGA2 antibody (ABIN8000311) specifically detects ITGA2 in FACS. The antibody is reactive with Human samples.

Quick Overview for ITGA2 antibody (AA 285-1181) (Fluoro550) (ABIN8000311)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA2 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-ITGA2 Antibody (Fluoro550)

Binding Specificity: AA 285-1181

Purpose: Anti-Integrin alpha 2/ITGA2 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Integrin alpha 2/ITGA2 recombinant protein (Position: E285-S1181).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2

Background:

Background: Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a protein which in humans is encoded by the CD49b gene. This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Gene Full Name: integrin subunit alpha 2

Gene ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex