ITGA2 antibody (AA 285-1181)

Catalog No. ABIN8000318

This Rabbit Polyclonal antibody specifically detects ITGA2 in FACS, WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ITGA2 antibody (AA 285-1181) (ABIN8000318)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-ITGA2 Antibody

Binding Specificity: AA 285-1181

Purpose: Anti-Integrin alpha 2/ITGA2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Integrin alpha 2/ITGA2 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Integrin alpha 2/ITGA2 recombinant protein (Position: E285-S1181).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2

Background:

Background: Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a protein which in humans is encoded by the CD49b gene. This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Gene Full Name: integrin subunit alpha 2

Molecular Weight: 165 kDa

Gene ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex