ICAM5 antibody (AA 27-392) (Fluoro550)

Catalog No. ABIN8000927

This Rabbit Polyclonal antibody specifically detects ICAM5 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ICAM5 antibody (AA 27-392) (Fluoro550) (ABIN8000927)

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM5 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-ICAM5 Antibody (Fluoro550)

Binding Specificity: AA 27-392

Purpose: Anti-ICAM5 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PAAF1 recombinant protein (Position: H27-L392).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ICAM5

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Alternative Name: ICAM5

Background:

Background: Intercellular adhesion molecule 5 is a protein that in humans is encoded by the ICAM5 gene. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

Gene Full Name: intercellular adhesion molecule 5

Gene ID: 7087

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location