IL-13 antibody (Middle Region) (Biotin)

Catalog No. ABIN8001870

The Rabbit Polyclonal anti-IL-13 antibody is suitable to detect IL-13 in samples from Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for IL-13 antibody (Middle Region) (Biotin) (ABIN8001870)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-13 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IL-13 Antibody (Biotin)

Binding Specificity: Middle Region

Purpose: Anti-Interleukin-13 IL13 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of rat IL-13.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Alternative Name: IL13

Background:

Background: IL-13, < a href=https://www.bosterbio.com/anti-il-13-antibody-pa1469-boster.html style=color:#EA8D28>Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells that is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ralpha) and at least one of two known IL-13-specific binding chains. IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Gene Full Name: interleukin 13

Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.

Gene ID: 116553

UniProt: P42203

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport