IL17RA antibody (AA 53-284) (HRP)

Catalog No. ABIN8001953

This Rabbit Polyclonal antibody specifically detects IL17RA in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for IL17RA antibody (AA 53-284) (HRP) (ABIN8001953)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IL17RA Antibody (HRP)

Binding Specificity: AA 53-284

Purpose: Anti-L17A Receptor/IL17RA Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human IL17RA recombinant protein (Position: K53-Q284). Human IL17RA shares 74.1% amino acid (aa) sequence identity with mouse IL17RA.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL17RA recombinant protein (Position: K53-Q284). Human IL17RA shares 74.1% amino acid (aa) sequence identity with mouse IL17RA.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL17RA

Background:

Background: Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.

Gene Full Name: interleukin 17 receptor A

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome