IL17RA antibody (AA 53-284) (Fluoro647)

Catalog No. ABIN8001956

This Rabbit Polyclonal antibody specifically detects IL17RA in FACS. It exhibits reactivity toward Human.

Quick Overview for IL17RA antibody (AA 53-284) (Fluoro647) (ABIN8001956)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-IL17RA Antibody (Fluoro647)

Binding Specificity: AA 53-284

Purpose: Anti-L17A Receptor/IL17RA Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human IL17RA recombinant protein (Position: K53-Q284). Human IL17RA shares 74.1% amino acid (aa) sequence identity with mouse IL17RA.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL17RA recombinant protein (Position: K53-Q284). Human IL17RA shares 74.1% amino acid (aa) sequence identity with mouse IL17RA.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL17RA

Background:

Background: Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.

Gene Full Name: interleukin 17 receptor A

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome