IL17C antibody (AA 19-197) (Fluoro488)

Catalog No. ABIN8002026

The Rabbit Polyclonal anti-IL17C antibody is suitable to detect IL17C in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for IL17C antibody (AA 19-197) (Fluoro488) (ABIN8002026)

Target: IL17C (Interleukin 17C (IL17C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17C antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-IL17C Antibody (Fluoro488)

Binding Specificity: AA 19-197

Purpose: Anti-IL17C Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL17C recombinant protein (Position: H19-V197).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL17C

Target: IL17C (Interleukin 17C (IL17C))

Alternative Name: IL17C

Background:

Background: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.

Gene Full Name: interleukin 17C

Gene ID: 27189

UniProt: Q9P0M4

Pathways: Cellular Response to Molecule of Bacterial Origin