IL17C antibody (AA 19-197) (HRP)

Catalog No. ABIN8002030

The HRP-conjugated Rabbit Polyclonal anti-IL17C antibody (ABIN8002030) specifically detects IL17C in WB, IHC and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for IL17C antibody (AA 19-197) (HRP) (ABIN8002030)

Target: IL17C (Interleukin 17C (IL17C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17C antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IL17C Antibody (HRP)

Binding Specificity: AA 19-197

Purpose: Anti-IL17C Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL17C recombinant protein (Position: H19-V197).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL17C

Target: IL17C (Interleukin 17C (IL17C))

Alternative Name: IL17C

Background:

Background: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.

Gene Full Name: interleukin 17C

Gene ID: 27189

UniProt: Q9P0M4

Pathways: Cellular Response to Molecule of Bacterial Origin