IL23R antibody (Fluoro647)

Catalog No. ABIN8002396

The Fluoro647-conjugated Rabbit Polyclonal anti-IL23R antibody (ABIN8002396) specifically detects IL23R in FACS. The antibody is reactive with Human samples.

Quick Overview for IL23R antibody (Fluoro647) (ABIN8002396)

Target: IL23R (Interleukin 23 Receptor (IL23R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23R antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-IL23R Antibody (Fluoro647)

Purpose: Anti-IL23 Receptor/IL23R Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IL23 Receptor/IL23R recombinant protein (Position: Q76-Q 305).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL23R

Target: IL23R (Interleukin 23 Receptor (IL23R))

Alternative Name: IL23R

Background:

Background: Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Gene Full Name: interleukin 23 receptor

Gene ID: 149233

UniProt: Q5VWK5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation