IL-7 antibody (AA 26-177) (HRP)

Catalog No. ABIN8002811

This Rabbit Polyclonal antibody specifically detects IL-7 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for IL-7 antibody (AA 26-177) (HRP) (ABIN8002811)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-7 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IL-7 Antibody (HRP)

Binding Specificity: AA 26-177

Purpose: Anti-IL7 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human IL7 recombinant protein (Position: D26-H177). Human IL7 shares 56.4%,57% amino acid (aa) sequence identity with mouse,rat IL7,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL7 recombinant protein (Position: D26-H177). Human IL7 shares 56.4% and 57% amino acid (aa) sequence identity with mouse and rat IL7, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL-7

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Alternative Name: IL7

Background:

Background: IL-7, Interleukin 7, is a protein that in humans is encoded by the IL-7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells in the red marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by lymphocytes. By the combination of approaches, IL-7 is located on 8q12-q13. IL-7 is critical for early T-cell development and homeostasis of naive and memory CD8-positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain is critical for early T-cell development and homeostasis of naive and memory CD8 -positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain.

Gene Full Name: interleukin 7

Sequence Similarities: Belongs to the IL-7/IL-9 family.

Gene ID: 3574

UniProt: P13232

Pathways: JAK-STAT Signaling