IL-7 antibody (AA 26-154) (HRP)

Catalog No. ABIN8002822

The HRP-conjugated Rabbit Polyclonal anti-IL-7 antibody (ABIN8002822) specifically detects IL-7 in WB, IHC and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for IL-7 antibody (AA 26-154) (HRP) (ABIN8002822)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-7 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IL-7 Antibody (HRP)

Binding Specificity: AA 26-154

Purpose: Anti-IL7 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived mouse IL7 recombinant protein (Position: E26-I154). Mouse IL7 shares 56.4%,87.6% amino acid (aa) sequence identity with human,rat IL7,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse IL7 recombinant protein (Position: E26-I154). Mouse IL7 shares 56.4% and 87.6% amino acid (aa) sequence identity with human and rat IL7, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL-7

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Alternative Name: Il7

Background:

Background: Interleukin 7  (IL-7) is a protein that in humans is encoded by the IL7 gene. The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. And it is found to be a cofactor for V (D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. In addition, this cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Gene Full Name: interleukin 7

Gene ID: 16196

UniProt: P10168

Pathways: JAK-STAT Signaling