IL-7 antibody (AA 26-177) (Fluoro594)

Catalog No. ABIN8002831

The Fluoro594-conjugated Rabbit Polyclonal anti-IL-7 antibody (ABIN8002831) specifically detects IL-7 in FACS. The antibody is reactive with Human samples.

Quick Overview for IL-7 antibody (AA 26-177) (Fluoro594) (ABIN8002831)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-7 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-IL-7 Antibody (Fluoro594)

Binding Specificity: AA 26-177

Purpose: Anti-Interleukin-7 IL7 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL-7 recombinant protein (Position: D26-H177).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL-7

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Alternative Name: IL7

Background:

Background: IL-7, Interleukin 7, is a protein that in humans is encoded by the IL-7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells in the red marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by lymphocytes. By the combination of approaches, IL-7 is located on 8q12-q13. IL-7 is critical for early T-cell development and homeostasis of naive and memory CD8-positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain is critical for early T-cell development and homeostasis of naive and memory CD8 -positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain.

Gene Full Name: interleukin 7

Sequence Similarities: Belongs to the IL-7/IL-9 family.

Gene ID: 3574

UniProt: P13232

Pathways: JAK-STAT Signaling