IL-7 antibody (AA 26-177) (HRP)

Catalog No. ABIN8002833

The Rabbit Polyclonal anti-IL-7 antibody is suitable to detect IL-7 in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for IL-7 antibody (AA 26-177) (HRP) (ABIN8002833)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-7 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IL-7 Antibody (HRP)

Binding Specificity: AA 26-177

Purpose: Anti-Interleukin-7 IL7 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL-7 recombinant protein (Position: D26-H177).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL-7

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Alternative Name: IL7

Background:

Background: IL-7, Interleukin 7, is a protein that in humans is encoded by the IL-7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells in the red marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by lymphocytes. By the combination of approaches, IL-7 is located on 8q12-q13. IL-7 is critical for early T-cell development and homeostasis of naive and memory CD8-positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain is critical for early T-cell development and homeostasis of naive and memory CD8 -positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain.

Gene Full Name: interleukin 7

Sequence Similarities: Belongs to the IL-7/IL-9 family.

Gene ID: 3574

UniProt: P13232

Pathways: JAK-STAT Signaling