INA antibody (AA 71-161) (APC)

Catalog No. ABIN8003032

The APC-conjugated Rabbit Polyclonal anti-INA antibody (ABIN8003032) specifically detects INA in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for INA antibody (AA 71-161) (APC) (ABIN8003032)

Target: INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INA antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-INA Antibody (APC)

Binding Specificity: AA 71-161

Purpose: Anti-Alpha Internexin/INA Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Alpha Internexin shares 98.9% amino acid (aa) sequence identity with both mouse,rat Alpha Internexin.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Alpha Internexin recombinant protein (Position: A71-R161). Human Alpha Internexin shares 98.9% amino acid (aa) sequence identity with both mouse and rat Alpha Internexin.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for INA

Target: INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))

Alternative Name: INA

Background:

Background: Alpha-Internexin (INA, also NF-66) is a 66 kDa member of the intermediate filament (IF) protein family. The protein was originally purified from rat optic nerve and spinal cord. And the protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in developing neuroblasts and in the Central Nervous System of adults. Meanwhile, the protein is a major component of the intermediate filament network in small interneurons and cerebellar granule cells, where it is present in the parallel fibers.

Gene Full Name: internexin neuronal intermediate filament protein alpha

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Gene ID: 9118

UniProt: Q16352