IDH3G antibody (AA 92-420) (PE)

Catalog No. ABIN8003473

The PE-conjugated Rabbit Polyclonal anti-IDH3G antibody (ABIN8003473) specifically detects IDH3G in FACS. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for IDH3G antibody (AA 92-420) (PE) (ABIN8003473)

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDH3G antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-IDH3G Antibody (PE)

Binding Specificity: AA 92-420

Purpose: Anti-IDH3G Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PAIP1 shares 97.6% amino acid (aa) sequence identity with mouse PAIP1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PAIP1 recombinant protein (Position: R92-Q420). Human PAIP1 shares 97.6% amino acid (aa) sequence identity with mouse PAIP1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IDH3G

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Alternative Name: IDH3G

Background:

Background: Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial is an enzyme that in humans is encoded by the IDH3G gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Gene Full Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma

Gene ID: 3421

UniProt: P51553