ICMT antibody (AA 13-284)

Catalog No. ABIN8003519

This Rabbit Polyclonal antibody specifically detects ICMT in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for ICMT antibody (AA 13-284) (ABIN8003519)

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICMT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-ICMT Antibody

Binding Specificity: AA 13-284

Purpose: Anti-ICMT Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human ICMT shares 96.3%,95.2% amino acid (aa) sequence identity with mouse,rat ICMT,respectively.

Characteristics: Anti-ICMT Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ICMT recombinant protein (Position: E13-L284). Human ICMT shares 96.3% and 95.2% amino acid (aa) sequence identity with mouse and rat ICMT, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ICMT

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Alternative Name: ICMT

Background:

Background: Protein-S-isoprenylcysteine O-methyltransferase is an enzyme that in humans is encoded by the ICMT gene. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

Gene Full Name: isoprenylcysteine carboxyl methyltransferase

Molecular Weight: 32 kDa

Gene ID: 23463

UniProt: O60725