Kallikrein 7 antibody (AA 30-238) (Fluoro488)

Catalog No. ABIN8003918

This Rabbit Polyclonal antibody specifically detects Kallikrein 7 in FACS. It exhibits reactivity toward Rat.

Quick Overview for Kallikrein 7 antibody (AA 30-238) (Fluoro488) (ABIN8003918)

Target: Kallikrein 7 (KLK7)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 7 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Kallikrein 7 Antibody (Fluoro488)

Binding Specificity: AA 30-238

Purpose: Anti-Klk7 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived rat Klk7 recombinant protein (Position: K30-N238).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Kallikrein 7

Target: Kallikrein 7 (KLK7)

Alternative Name: Klk7

Background:

Background: Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 is a chymotrypsin-like serine protease of the member of peptidase S1 family. It is synthesized with a signal peptide of 22 amino acids (aa 1-22) and a propeptide region (aa 23-29) that are subsequently cleaved to generate the mature form. Human KLK7 displays about 40 to 60 % amino acid homology with other members of the family. It cleaves proteins with aromatic side chains in the P1 position. KLK7 is abundantly expressed in the skin and is also present in the brain, mammary gland, cerebellum, spinal cord, and kidney. Lower levels of expression have been reported in in salivary glands, uterus, thymus, thyroid, placenta, trachea, and testis. Its levels are shown to be up-regulated in ovarian carcinoma, especially late-stage serous carcinoma. Less differentiated tumors of more advanced stage show higher level KLK7 expression. KLK7 activity is inhibited by zinc and copper ions

Gene Full Name: kallikrein 1

Gene ID: 292852

UniProt: P36373

Pathways: Complement System