Kallikrein 4 antibody (AA 31-254) (Fluoro594)

Catalog No. ABIN8003953

The Fluoro594-conjugated Rabbit Polyclonal anti-Kallikrein 4 antibody (ABIN8003953) specifically detects Kallikrein 4 in FACS. The antibody is reactive with Human samples.

Quick Overview for Kallikrein 4 antibody (AA 31-254) (Fluoro594) (ABIN8003953)

Target: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 4 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Kallikrein 4 Antibody (Fluoro594)

Binding Specificity: AA 31-254

Purpose: Anti-Kallikrein 4/KLK4 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Kallikrein 4

Target: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Alternative Name: KLK4

Background:

Background: Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.

Gene Full Name: kallikrein related peptidase 4

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

Gene ID: 9622

UniProt: Q9Y5K2

Pathways: Complement System