KIF7 antibody (Middle Region) (Fluoro550)

Catalog No. ABIN8004513

The Rabbit Polyclonal anti-KIF7 antibody is suitable to detect KIF7 in samples from Human. It has been validated for FACS.

Quick Overview for KIF7 antibody (Middle Region) (Fluoro550) (ABIN8004513)

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF7 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-KIF7 Antibody (Fluoro550)

Binding Specificity: Middle Region

Purpose: Anti-KIF7 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human KIF7, identical to the related mouse sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Alternative Name: KIF7

Background:

Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Gene Full Name: kinesin family member 7

Gene ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signaling