KIF7 antibody (Middle Region)

Catalog No. ABIN8004520

The Rabbit Polyclonal anti-KIF7 antibody (ABIN8004520) specifically detects KIF7 in WB. The antibody is reactive with Human samples.

Quick Overview for KIF7 antibody (Middle Region) (ABIN8004520)

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF7 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-KIF7 Antibody

Binding Specificity: Middle Region

Purpose: Anti-KIF7 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequences.

Characteristics: Anti-KIF7 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human KIF7, identical to the related mouse sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Alternative Name: KIF7

Background:

Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Gene Full Name: kinesin family member 7

Molecular Weight: 151 kDa

Gene ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signaling