KISS1R antibody (Middle Region)

Catalog No. ABIN8004609

The Rabbit Polyclonal anti-KISS1R antibody is suitable to detect KISS1R in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for KISS1R antibody (Middle Region) (ABIN8004609)

Target: KISS1R (KISS1 Receptor (KISS1R))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KISS1R antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-KISS1R Antibody

Binding Specificity: Middle Region

Purpose: Anti-KiSS1 receptor/KISS1R Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-KiSS1 receptor/KISS1R Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human KiSS1 receptor, which shares 82.4% amino acid (aa) sequence identity with both mouse and rat KiSS1 receptor.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Alternative Name: KISS1R

Background:

Background: The KiSS1-derived peptide receptor (also known as GPR54 or the Kisspeptin receptor) is a G protein-coupled receptor which binds the peptide hormone kisspeptin (metastin). Kisspeptin is involved in the regulation of endocrine function and the onset of puberty, with activation of the kisspeptin receptor triggering release of gonadotropin-releasing hormone (GnRH), and release of kisspeptin itself being inhibited by oestradiol but enhanced by GnRH. Reductions in kisspeptin levels with age may conversely be one of the reasons behind age-related declines in levels of other endocrine hormones such as luteinizing hormone.

Gene Full Name: KISS1 receptor

Molecular Weight: 43 kDa

Gene ID: 84634

UniProt: Q969F8