LGI4 antibody (AA 225-531) (HRP)

Catalog No. ABIN8005706

This Rabbit Polyclonal antibody specifically detects LGI4 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LGI4 antibody (AA 225-531) (HRP) (ABIN8005706)

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGI4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-LGI4 Antibody (HRP)

Binding Specificity: AA 225-531

Purpose: Anti-LGI4 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LGI4 recombinant protein (Position: E225-H531).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LGI4

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Alternative Name: LGI4

Background:

Background: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs). Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with autodominant lateral temporal epilepsy (ADTLE). However, the LGI4 gene is located in a region linked to benign familial infantile convulsions and a GC-to-AT polymorphism in LGI4 was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.

Gene Full Name: leucine rich repeat LGI family member 4

Gene ID: 163175

UniProt: Q8N135