LGI4 antibody (AA 225-531) (PE)

Catalog No. ABIN8005708

The PE-conjugated Rabbit Polyclonal anti-LGI4 antibody (ABIN8005708) specifically detects LGI4 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for LGI4 antibody (AA 225-531) (PE) (ABIN8005708)

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGI4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-LGI4 Antibody (PE)

Binding Specificity: AA 225-531

Purpose: Anti-LGI4 Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LGI4 recombinant protein (Position: E225-H531).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LGI4

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Alternative Name: LGI4

Background:

Background: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs). Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with autodominant lateral temporal epilepsy (ADTLE). However, the LGI4 gene is located in a region linked to benign familial infantile convulsions and a GC-to-AT polymorphism in LGI4 was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.

Gene Full Name: leucine rich repeat LGI family member 4

Gene ID: 163175

UniProt: Q8N135