LGI4 antibody (AA 225-531)

Catalog No. ABIN8005710

The Rabbit Polyclonal anti-LGI4 antibody is suitable to detect LGI4 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC, FACS, IF and ICC.

Quick Overview for LGI4 antibody (AA 225-531) (ABIN8005710)

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGI4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-LGI4 Antibody

Binding Specificity: AA 225-531

Purpose: Anti-LGI4 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-LGI4 Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LGI4 recombinant protein (Position: E225-H531).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LGI4

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Alternative Name: LGI4

Background:

Background: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs). Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with autodominant lateral temporal epilepsy (ADTLE). However, the LGI4 gene is located in a region linked to benign familial infantile convulsions and a GC-to-AT polymorphism in LGI4 was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.

Gene Full Name: leucine rich repeat LGI family member 4

Molecular Weight: 59 kDa

Gene ID: 163175

UniProt: Q8N135