SHoc2/Sur8 antibody (AA 119-542) (APC)

Catalog No. ABIN8005718

This Rabbit Polyclonal antibody specifically detects SHoc2/Sur8 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SHoc2/Sur8 antibody (AA 119-542) (APC) (ABIN8005718)

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHoc2/Sur8 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-SHoc2/Sur8 Antibody (APC)

Binding Specificity: AA 119-542

Purpose: Anti-Shoc2/Sur8 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Shoc2/Sur8 recombinant protein (Position: I119-K542).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SHoc2/Sur8

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Alternative Name: SHOC2

Background:

Background: Leucine-rich repeat protein SHOC-2 is a protein that in humans is encoded by the SHOC2 gene. This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.

Gene Full Name: SHOC2 leucine rich repeat scaffold protein

Gene ID: 8036

UniProt: Q9UQ13