Lrig1 antibody (AA 79-906) (Fluoro488)

Catalog No. ABIN8005768

The Fluoro488-conjugated Rabbit Polyclonal anti-Lrig1 antibody (ABIN8005768) specifically detects Lrig1 in FACS. The antibody is reactive with Human samples.

Quick Overview for Lrig1 antibody (AA 79-906) (Fluoro488) (ABIN8005768)

Target: Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lrig1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Lrig1 Antibody (Fluoro488)

Binding Specificity: AA 79-906

Purpose: Anti-LRIG1 Antibody Fluoro488 Conjugated

Predicted Reactivity: Human LRIG1 shares 89.8% amino acid (aa) sequence identity with mouse LRIG1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LRIG1 recombinant protein (Position: K79-E906). Human LRIG1 shares 89.8% amino acid (aa) sequence identity with mouse LRIG1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Lrig1

Target: Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))

Alternative Name: LRIG1

Background:

Background: Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It is mapped to 3p14.1. Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family, MET and RET. This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

Gene Full Name: leucine rich repeats and immunoglobulin like domains 1

Gene ID: 26018

UniProt: Q96JA1