LTK antibody (C-Term) (Fluoro594)

Catalog No. ABIN8005902

The Rabbit Polyclonal anti-LTK antibody is suitable to detect LTK in samples from Human. It has been validated for FACS.

Quick Overview for LTK antibody (C-Term) (Fluoro594) (ABIN8005902)

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTK antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-LTK Antibody (Fluoro594)

Binding Specificity: C-Term

Purpose: Anti-LTK Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LTK.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LTK

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Alternative Name: LTK

Background:

Background: LTK (Leukocyte Tyrosine Kinase), also known as TYK1, is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Toyoshima et al. (1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs. Liao et al. (1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2. Thus, the LTK gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions.

Gene Full Name: leukocyte receptor tyrosine kinase

Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

Gene ID: 4058

UniProt: P29376

Pathways: RTK Signaling