LAIR1 antibody (AA 142-287) (Fluoro647)

Catalog No. ABIN8005918

The Fluoro647-conjugated Rabbit Polyclonal anti-LAIR1 antibody (ABIN8005918) specifically detects LAIR1 in FACS. The antibody is reactive with Human samples.

Quick Overview for LAIR1 antibody (AA 142-287) (Fluoro647) (ABIN8005918)

Target: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAIR1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-LAIR1 Antibody (Fluoro647)

Binding Specificity: AA 142-287

Purpose: Anti-LAIR1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LAIR1 recombinant protein (Position: Q142-H287).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LAIR1

Target: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Alternative Name: LAIR1

Background:

Background: Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene. The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

Gene Full Name: leukocyte associated immunoglobulin like receptor 1

Gene ID: 3903

UniProt: Q6GTX8