Leupaxin antibody (N-Term) (APC)

Catalog No. ABIN8005949

This Rabbit Polyclonal antibody specifically detects Leupaxin in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for Leupaxin antibody (N-Term) (APC) (ABIN8005949)

Target: Leupaxin (LPXN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leupaxin antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Leupaxin Antibody (APC)

Binding Specificity: N-Term

Purpose: Anti-Leupaxin/LPXN Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related rat sequence by two amino acids,and from the related mouse sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Leupaxin, different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Leupaxin

Target: Leupaxin (LPXN)

Alternative Name: LPXN

Background:

Background: Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity.

Gene Full Name: leupaxin

Sequence Similarities: Belongs to the paxillin family.

Gene ID: 9404

UniProt: O60711