LASP1 antibody (C-Term) (HRP)

Catalog No. ABIN8006025

The Rabbit Polyclonal anti-LASP1 antibody is suitable to detect LASP1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for LASP1 antibody (C-Term) (HRP) (ABIN8006025)

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASP1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-LASP1 Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-LIM and SH3 domain protein 1 LASP1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LASP1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LASP1

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Alternative Name: LASP1

Background:

Background: LASP1 (LIM and SH3 domain protein 1), also known as LASP1, is a protein that in humans is encoded by the LASP1 gene. This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. LASP1 has been shown to interact with Zyxin. Tomasetto et al. (1995) mapped the LASP1 gene to chromosome 17q11-q21.3 by radioactive in situ hybridization. Northern blot analysis revealed that LASP1 mRNA was expressed at a basal level in all normal tissues examined and overexpressed in 8 % of primary breast cancers. In most of these cancers, LASP1 and ERBB2 were simultaneously overexpressed.

Gene Full Name: LIM and SH3 protein 1

Sequence Similarities: Contains 1 LIM zinc-binding domain.

Gene ID: 3927

UniProt: Q14847