HSD3B1 antibody

Catalog No. ABIN750943

This Rabbit Polyclonal antibody specifically detects HSD3B1 in WB, IHC (p), IF (p). It exhibits reactivity toward Human, Rat, Mouse.

Quick Overview for HSD3B1 antibody (ABIN750943)

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD3B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HSD3B1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSD3B1

Isotype: IgG

Application Details

Application Notes: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HSD3B1

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Alternative Name: Hsd3b1

Background:

Synonyms: 3 beta and steroid delta isomerase 1, 3 beta and steroid hydroxy delta 5 steroid dehydrogenase, 3 beta HSD I, 3BH, 3BHSD, HGNC:5217, HSD3B, HSD3B1, HSDB3, HSDB3A, Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1, Hydroxy delta 5 steroid dehydrogenase, trophoblast antigen.

Background: HSD3B1 (3-beta hydroxysteroid dehydrogenase) is a bifunctional enzyme that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.There are two HSD3B1 proteins, type I and type II. Expressed by different genes, they function in different areas of the body. HSD3B1 has been shown to be a highly specific and sensitive trophoblast-associated marker.

Gene ID: 3283

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis