HSD3B1 antibody (Biotin)

Catalog No. ABIN750945

The Biotin-conjugated Rabbit Polyclonal anti-HSD3B1 antibody (ABIN750945) specifically detects HSD3B1 in WB and IHC (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HSD3B1 antibody (Biotin) (ABIN750945)

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD3B1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HSD3B1 Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSD3B1

Isotype: IgG

Application Details

Application Notes: WB(1:100-1000), IHC-P(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HSD3B1

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Alternative Name: Hsd3b1

Background:

Synonyms: 3 beta and steroid delta isomerase 1, 3 beta and steroid hydroxy delta 5 steroid dehydrogenase, 3 beta HSD I, 3BH, 3BHSD, HGNC:5217, HSD3B, HSD3B1, HSDB3, HSDB3A, Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1, Hydroxy delta 5 steroid dehydrogenase, trophoblast antigen.

Background: HSD3B1 (3-beta hydroxysteroid dehydrogenase) is a bifunctional enzyme that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.There are two HSD3B1 proteins, type I and type II. Expressed by different genes, they function in different areas of the body. HSD3B1 has been shown to be a highly specific and sensitive trophoblast-associated marker.

Gene ID: 3283

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis