LOXL1 antibody (C-Term) (Cy3)

Catalog No. ABIN8007132

The Rabbit Polyclonal anti-LOXL1 antibody is suitable to detect LOXL1 in samples from Human. It has been validated for FACS.

Quick Overview for LOXL1 antibody (C-Term) (Cy3) (ABIN8007132)

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-LOXL1 Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-LOXL1 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LOXL1

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Alternative Name: LOXL1

Background:

Background: Lysyl oxidase homolog 1, also known as?LOXL1, is an?enzyme?which in humans is encoded by the?LOXL1?gene. This gene encodes a member of the?lysyl oxidase?gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in?collagens?and?elastin. A highly conserved amino acid sequence at the C-terminus?end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The?N-terminus?is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and?chemotaxis?to each member of the family.

Gene Full Name: lysyl oxidase like 1

Gene ID: 4016

UniProt: Q08397