MED20 antibody (AA 1-212) (APC)

Catalog No. ABIN8008612

The APC-conjugated Rabbit Polyclonal anti-MED20 antibody (ABIN8008612) specifically detects MED20 in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MED20 antibody (AA 1-212) (APC) (ABIN8008612)

Target: MED20 (Mediator Complex Subunit 20 (MED20))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED20 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-MED20 Antibody (APC)

Binding Specificity: AA 1-212

Purpose: Anti-TRFP/MED20 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TRFP / MED20 recombinant protein (Position: M1-R212).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MED20

Target: MED20 (Mediator Complex Subunit 20 (MED20))

Alternative Name: MED20

Background:

Background: MED20 is a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder.

Gene Full Name: mediator complex subunit 20

Gene ID: 9477

UniProt: Q9H944

Pathways: Regulation of Lipid Metabolism by PPARalpha