MC3R antibody (N-Term) (Fluoro550)

Catalog No. ABIN8008839

The Rabbit Polyclonal anti-MC3R antibody is suitable to detect MC3R in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for MC3R antibody (N-Term) (Fluoro550) (ABIN8008839)

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC3R antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-MC3R Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-MC3 Receptor/MC3R Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by six amino acids,and from the related rat sequence by seven amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MC3 Receptor, different from the related mouse sequence by six amino acids, and from the related rat sequence by seven amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MC3R

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Alternative Name: MC3R

Background:

Background: Melanocortin receptor 3 is a protein that in humans is encoded by the MC3R gene. It is mapped to 20q13.2. This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.

Gene Full Name: melanocortin 3 receptor

UniProt: P41968

Pathways: cAMP Metabolic Process