NG2 antibody (AA 962-1194) (Fluoro550)

Catalog No. ABIN8008894

The Fluoro550-conjugated Rabbit Polyclonal anti-NG2 antibody (ABIN8008894) specifically detects NG2 in FACS. The antibody is reactive with Human samples.

Quick Overview for NG2 antibody (AA 962-1194) (Fluoro550) (ABIN8008894)

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NG2 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-NG2 Antibody (Fluoro550)

Binding Specificity: AA 962-1194

Purpose: Anti-NG2/CSPG4 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NG2/CSPG4 recombinant protein (Position: N962-D1194).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NG2

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Alternative Name: CSPG4

Background:

Background: Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that in humans is encoded by the CSPG4 gene. CSPG4 plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. It represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

Gene Full Name: chondroitin sulfate proteoglycan 4

Gene ID: 1464

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process