Mesp2 antibody (AA 1-397) (Fluoro488)

Catalog No. ABIN8009212

The Fluoro488-conjugated Rabbit Polyclonal anti-Mesp2 antibody (ABIN8009212) specifically detects Mesp2 in FACS. The antibody is reactive with Human samples.

Quick Overview for Mesp2 antibody (AA 1-397) (Fluoro488) (ABIN8009212)

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mesp2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Mesp2 Antibody (Fluoro488)

Binding Specificity: AA 1-397

Purpose: Anti-Mesp2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Mesp2 recombinant protein (Position: M1-Y397).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Alternative Name: MESP2

Background:

Background: Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene. This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Gene Full Name: mesoderm posterior bHLH transcription factor 2

Gene ID: 145873

UniProt: Q0VG99