MEPCE antibody (AA 79-651) (Biotin)

Catalog No. ABIN8009716

The Biotin-conjugated Rabbit Polyclonal anti-MEPCE antibody (ABIN8009716) specifically detects MEPCE in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MEPCE antibody (AA 79-651) (Biotin) (ABIN8009716)

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEPCE antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MEPCE Antibody (Biotin)

Binding Specificity: AA 79-651

Purpose: Anti-MEPCE Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MEPCE shares 90.4% amino acid (aa) sequence identity with mouse MEPCE.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MEPCE recombinant protein (Position: G79-L651). Human MEPCE shares 90.4% amino acid (aa) sequence identity with mouse MEPCE.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MEPCE

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Alternative Name: MEPCE

Background:

Background: Enables 7SK snRNA binding activity and RNA 5'-gamma-phosphate methyltransferase activity. Involved in RNA modification, positive regulation of protein localization to Cajal body, and positive regulation of snRNA transcription by RNA polymerase II. Located in nucleus. Part of 7SK snRNP.

Gene Full Name: methylphosphate capping enzyme

Gene ID: 56257

UniProt: Q7L2J0

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection