MVD antibody (N-Term) (Fluoro550)

Catalog No. ABIN8009851

The Fluoro550-conjugated Rabbit Polyclonal anti-MVD antibody (ABIN8009851) specifically detects MVD in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MVD antibody (N-Term) (Fluoro550) (ABIN8009851)

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVD antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-MVD Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-MVD Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MVD, which shares 97.3% amino acid (aa) sequence identity with both mouse and rat MVD.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MVD

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Alternative Name: MVD

Background:

Background: The enzyme mevalonate pyrophosphate decarboxylase (MVD, EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVDsequence.

Gene Full Name: mevalonate diphosphate decarboxylase

UniProt: P53602