MVD antibody (AA 62-374) (Biotin)

Catalog No. ABIN8009859

The Rabbit Polyclonal anti-MVD antibody is suitable to detect MVD in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for MVD antibody (AA 62-374) (Biotin) (ABIN8009859)

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVD antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MVD Antibody (Biotin)

Binding Specificity: AA 62-374

Purpose: Anti-MVD Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MVD recombinant protein (Position: E62-Q374).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MVD

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Alternative Name: MVD

Background:

Background: The enzyme mevalonate pyrophosphate decarboxylase (MVD, EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVDsequence.

Gene Full Name: mevalonate diphosphate decarboxylase

Gene ID: 4597

UniProt: P53602