MVD antibody (AA 62-374)

Catalog No. ABIN8009869

The Rabbit Polyclonal anti-MVD antibody (ABIN8009869) specifically detects MVD in WB, ELISA, IHC and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for MVD antibody (AA 62-374) (ABIN8009869)

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-MVD Antibody

Binding Specificity: AA 62-374

Purpose: Anti-MVD Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-MVD Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MVD recombinant protein (Position: E62-Q374).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MVD

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Alternative Name: MVD

Background:

Background: The enzyme mevalonate pyrophosphate decarboxylase (MVD, EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVDsequence.

Gene Full Name: mevalonate diphosphate decarboxylase

Molecular Weight: 43 kDa

Gene ID: 4597

UniProt: P53602