MAPK13 antibody (AA 328-365) (Fluoro647)

Catalog No. ABIN8010947

This Rabbit Polyclonal antibody specifically detects MAPK13 in FACS. It exhibits reactivity toward Human.

Quick Overview for MAPK13 antibody (AA 328-365) (Fluoro647) (ABIN8010947)

Target: MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK13 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-MAPK13 Antibody (Fluoro647)

Binding Specificity: AA 328-365

Purpose: Anti-MAPK13 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human MAPK13 shares 94.7%,89.5% amino acid (aa) sequence identity with mouse,rat MAPK13,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAPK13 recombinant protein (Position: L328-L365). Human MAPK13 shares 94.7% and 89.5% amino acid (aa) sequence identity with mouse and rat MAPK13, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MAPK13

Target: MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))

Alternative Name: MAPK13

Background:

Background: Mitogen-activated protein kinase 13 (MAPK 13), also known as stress-activated protein kinase 4 (SAPK4), is an enzyme that in humans is encoded by the MAPK13 gene. This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.

Gene Full Name: mitogen-activated protein kinase 13

Gene ID: 5603

UniProt: O15264

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Hepatitis C, BCR Signaling, S100 Proteins