MOV10 antibody (AA 167-772) (APC)

Catalog No. ABIN8011572

The Rabbit Polyclonal anti-MOV10 antibody is suitable to detect MOV10 in samples from Human. It has been validated for FACS.

Quick Overview for MOV10 antibody (AA 167-772) (APC) (ABIN8011572)

Target: MOV10 (Moloney Leukemia Virus 10 (MOV10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOV10 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-MOV10 Antibody (APC)

Binding Specificity: AA 167-772

Purpose: Anti-MOV10 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MOV10 recombinant protein (Position: H167-Q772).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MOV10

Target: MOV10 (Moloney Leukemia Virus 10 (MOV10))

Alternative Name: MOV10

Background:

Background: Putative helicase MOV-10 is an enzyme that in humans is encoded by the MOV10 gene.MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). HumanMOV10may regulate a wide range of RNA viruses and could also control the retrotransposition of endogenous retroelements in mammals. MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection.MOV10 can potently inhibit HIV-1 replication at multiple stages. It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.

Gene Full Name: Mov10 RNA helicase

Gene ID: 4343

UniProt: Q9HCE1

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome