MYBL1 antibody (AA 199-752) (Fluoro488)

Catalog No. ABIN8012260

The Fluoro488-conjugated Rabbit Polyclonal anti-MYBL1 antibody (ABIN8012260) specifically detects MYBL1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MYBL1 antibody (AA 199-752) (Fluoro488) (ABIN8012260)

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBL1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-MYBL1 Antibody (Fluoro488)

Binding Specificity: AA 199-752

Purpose: Anti-v-Myb/MYBL1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human v-Myb/MYBL1 recombinant protein (Position: K199-L752).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MYBL1

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Alternative Name: MYBL1

Background:

Background: MYB proto-oncogene like 1 is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t (14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.

Gene Full Name: MYB proto-oncogene like 1

Gene ID: 4603

UniProt: P10243

Pathways: Cell Division Cycle, Chromatin Binding