MYBL1 antibody (AA 199-752)

Catalog No. ABIN8012268

The Rabbit Polyclonal anti-MYBL1 antibody is suitable to detect MYBL1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for MYBL1 antibody (AA 199-752) (ABIN8012268)

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-MYBL1 Antibody

Binding Specificity: AA 199-752

Purpose: Anti-v-Myb/MYBL1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-v-Myb/MYBL1 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human v-Myb/MYBL1 recombinant protein (Position: K199-L752).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MYBL1

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Alternative Name: MYBL1

Background:

Background: MYB proto-oncogene like 1 is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t (14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.

Gene Full Name: MYB proto-oncogene like 1

Molecular Weight: 86 kDa

Gene ID: 4603

UniProt: P10243

Pathways: Cell Division Cycle, Chromatin Binding