Myosin VI antibody (AA 383-786) (Fluoro488)

Catalog No. ABIN8012800

The Fluoro488-conjugated Rabbit Polyclonal anti-Myosin VI antibody (ABIN8012800) specifically detects Myosin VI in FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for Myosin VI antibody (AA 383-786) (Fluoro488) (ABIN8012800)

Target: Myosin VI (MYO6)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VI antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Myosin VI Antibody (Fluoro488)

Binding Specificity: AA 383-786

Purpose: Anti-MYO6 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MYO6 recombinant protein (Position: Q383-H786).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Myosin VI

Target: Myosin VI (MYO6)

Alternative Name: MYO6

Background:

Background: Unconventional myosin-VI, is a protein that in humans is coded for by MYO6. This gene encodes a reverse-ion motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: myosin VI

Gene ID: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization